Table 2.

Lateral prostate (T&E) pathology in d-200 rats.

$\mathrm{\mu g}/\mathrm{kg}\mathrm{BW}$	PIN			Hyperplasia		Inflammation
	Score	Incidence		Score	Incidence	Score	Incidence
		All	HGPIN
$\text{Vehicle}+\text{Empty}$	0.3	20%	0%	0.90	40%	0.00	0%
$\text{Vehicle}+\mathrm{T}\text{E}$	1.46	67%	33%	1.10	60%	0.89	67%
Low ${\text{E}}_2$	1.18	62%	25%	0.38	25%	1.38	75%
High ${\text{E}}_2$	2.46a,c	91%	73%c	0.73	64%	2.00b	100%
0.1 BPA	2.54a,c	100%	70%	0.80	60%	1.70a	90%
1.0 BPA	2.27c	89%	56%	0.56	67%	1.33	89%
10 BPA	2.54a,c	100%	67%	0.67	56%	2.22b	100%
100 BPA	2.18	75%	62%	0.62	38%	1.25	50%
5K BPA	2.75b,c	90%	80%a,c	0.80	80%c	1.90a	100%
(a) vs. $\text{Veh}+\mathrm{T}\text{E}$	$p<0.05$	NS	$p<0.05$	NS	NS	$p<0.05$	NS
(b) vs. $\text{Veh}+\mathrm{T}\mathrm{E}$	$p<0.01$					$p<0.01$
(c) vs. Low ${\text{E}}_2$	$p<0.05$		$p<0.05$		$p<0.05$

Note: Scores were analyzed by ANOVA with post hoc Dunnett multiple comparisons.

Incidence was analyzed by chi-square and Fischer’s exact test.

All PIN includes tissues with 1, 2, or 3 PIN scores.

HGPIN includes only 2 and 3 PIN scores. $n=8–11/\text{group}$; NS, nonsignificant.