Table 2.
Separation parameters reported for various ion mobility platforms. The “Reference Point” column references the annotations in Figure 4 and in Appendix S1 of the supporting information.
| First Author | Ref. Point | Percent Difference in CCS (%)1 | Reported Resolving Power (Rp) 2 | Calculated Resolving Power (Rp)3 | Experimental Resolution (Rpp)4 | Predicted Resolution (Rpp)5 | Percent Error in Resolution (%)6 | Dispersion Axis Projected in IM Spectra | |
|---|---|---|---|---|---|---|---|---|---|
| DTIMS | Groessl, M. | A | 0.4 | >250 | 332 | 0.84 | 0.78 | 7.3 | td (ms) |
| Groessl, M. | B | 0.8 | 250 | 268 | 1.38 | 1.26 | 8.3 | td (ms) | |
| Groessl, M. | C | [1.2] | [251] | 251 | 1.77 | 1.77 | −0.3 | td (ms) | |
| Asbury, G. R. | D | [1.2] | [130] | 131 | 0.76 | 0.93 | −22.2 | td (ms) | |
| Groessl, M. | E | 1.3 | [187] | 187 | 1.31 | 1.46 | −11.8 | td (ms) | |
| Pierson, G. U. | F | 1.7 | [66] | 66 | 0.65 | 0.65 | 0.1 | CCS (Å2) | |
| Tang, G. R. | G | 1.7 | [62] | 63 | 0.58 | 0.63 | −8.0 | td (ms) | |
| Dodds, J. N. | H | 2.3 | 58 | 58 | 0.79 | 0.79 | 0.1 | CCS (Å2) | |
| Gaye, M. M. | I | 2.6 | [83] | 83 | 1.26 | 1.26 | 0.0 | CCS (Å2) | |
| Adamov, A. | J | 3.2 | 77 | 72 | 1.46 | 1.46 | −0.2 | K 2 0 (cm/Vs) | |
|
| |||||||||
| TWIMS | Deng, L. | K | 0.4 | 124 | 342 | 0.71 | 0.26 | 63.1 | td (ms) |
| Giles, K. | L | 1.5 | – | [208] | 4.34 | 1.90 | 56.3 | td (ms) | |
| Giles, K. | M | 5.1 | 18 | 40 | 1.21 | 0.55 | 55.0 | td (ms) | |
| Giles, K. | N | 5.7 | 25 | 41 | 1.36 | 0.83 | 38.7 | td (ms) | |
| Hofmann, J. | O | 5.9 | 26 | 43 | 1.51 | 0.88 | 41.4 | td (ms) | |
|
| |||||||||
| TIMS | Silveira, J. A. | P | 1.0 | 154–183 | 178 | 1.05 | 1.06 | −0.3 | CCS (Å2) |
| Bruker | Q | 1.0 | [113] | 113 | 0.68 | 0.69 | −0.6 | K0 (cm2/Vs) | |
| Bruker | R | 1.7 | 185 | 177 | 1.74 | 1.74 | 0.1 | K0 (cm2/Vs) | |
|
| |||||||||
| OTHER | Barnett, D. A. | S | [1.0] | – | 130 | 0.83 | – | – | Voltage (V) |
| Lee, S. | T | 2.8 | [66] | 67 | 1.09 | 1.09 | 0.1 | Frequency (Hz) | |
| Glaskin, R. S. | U | 2.7 | 121 | 85 | 1.42 | 1.33 | 6.3 | Frequency (Hz) | |
| Glaskin, R. S. | V | 2.2 | 417 | 145 | 1.90 | 5.72 | 185 | Frequency (Hz) | |
1
Calculated from equation 4. Bracketed values were determined using CCS values obtained in the PI’s laboratory
2
Bracketed values were calculated from equation 1 using the dispersion axis provided.
3
Calculated from equation 1 using the CCS-based definition for Rp.
4
Calculated from equation 2 using the dispersion axis provided.
5
Calculated from equation 3 using the dispersion axis provided.
6
Calculated from equation 5.