Table 1.
Characteristic | Case | Control | ORa | 95% CI | |||
---|---|---|---|---|---|---|---|
% | % | ||||||
Age at enrollment in AMD study, y | |||||||
50–69 | 36 | 22 | 28,801 | 74 | 1.0 | Reference | |
70–79 | 82 | 51 | 8,286 | 21 | 7.9 | 5.3 | 11.7 |
43 | 27 | 2,021 | 5 | 17.5 | 11.2 | 27.3 | |
Gender | |||||||
Men | 95 | 59 | 22,658 | 58 | 1.0 | Reference | |
Women | 66 | 41 | 16,450 | 42 | 1.3 | 0.9 | 1.8 |
Race/ethnicity | |||||||
White, non-Hispanic | 158 | 98 | 37,984 | 97 | 1.0 | Reference | |
Other | 3 | 2 | 1,124 | 3 | 0.5 | 0.2 | 1.6 |
State | |||||||
Iowa | 95 | 59 | 25,612 | 65 | 1.0 | Reference | |
North Carolina | 66 | 41 | 13,496 | 35 | 0.9 | 0.7 | 1.3 |
Education | |||||||
92 | 59 | 19,877 | 54 | 1.0 | Reference | ||
64 | 41 | 17,046 | 46 | 1.3 | 0.9 | 1.8 | |
Ever smoker | |||||||
No | 75 | 47 | 23,292 | 60 | 1.0 | Reference | |
Yes | 86 | 53 | 15,816 | 40 | 1.8 | 1.3 | 2.5 |
Alcohol consumption (frequency) | |||||||
Never | 77 | 49 | 16,100 | 42 | 1.0 | Reference | |
to 3 times per mo | 41 | 26 | 13,471 | 35 | 1.0 | 0.7 | 1.4 |
Once a week or more | 38 | 24 | 8,530 | 22 | 1.3 | 0.9 | 2.0 |
BMI () | |||||||
54 | 34 | 12,123 | 32 | 1.0 | Reference | ||
25–30 | 78 | 50 | 17,139 | 45 | 1.0 | 0.7 | 1.5 |
25 | 16 | 87,98 | 23 | 0.7 | 0.5 | 1.2 |
Note: AMD, age-related macular degeneration; BMI, body mass index; CI, confidence interval; OR, odds ratio.
All models include age, gender, and smoking.