Table 4. Odds Ratios for a Rapid Annual Decrease in Lean Mass (Lowest Quartile^a).

	No. of subjects (%)	Model 1	Model 2	Model 3	Model 4
30s	8,361/53,829 (23.3)	1.000	1.000	1.000	1.000
40s	6,810/26,303 (25.9)	1.148 (1.106–1.191)	1.148 (1.106–1.191)	1.205 (1.143–1.271)	1.200 (1.134–1.270)
50s	1,038/3,135 (33.1)	1.626 (1.504–1.759)	1.627 (1.504–1.760)	1.576 (1.436–1.730)	1.573 (1.422–1.741)
≥60s	223/589 (37.9)	2.002 (1.692–2.369)	2.000 (1.690–2.367)	1.921 (1.585–2.328)	2.081 (1.678–2.581)

Model 1, no adjustment; Model 2, adjusted for sex, body mass index; Model 3, adjusted for model 2 plus fat mass, lean mass, glycated hemoglobin, and waist circumference; Model 4, model 3 plus exercise, alcohol drinking, and smoking status.

^aThe cutoffs for the lowest quartile groups are as follows: <−0.54% in men, <−0.67% in women.