Fig. 3. Effects of compound C (Cc) on serum leptin concentrations in refed groups of 30 (E-30) or 300 (E-300) rats. Bars depict mean serum leptin levels±SEM 1 hour after refeeding in the following groups: left-hand side of graph: full-fed (FF)-12/vehicle (V; open bars), 12 hours of food deprivation (FD-12)/V (horizontal bars), or FD-12/Cc (cross-hatched bars) groups of E-30 or E-300 rats (n=6 rats/group); and right-hand side of graph: FF-18/V (open bars), 18 hours of food deprivation (FD-18)/V (horizontal bars), or FD-18/Cc (cross-hatched bars) E-30 or E-300 rats (n=6 rats/group). ^aP<0.05 vs. FF.