Table 2.

Association between inflammation, pain and heart rate variability before and after multivariable adjustment.

	N	Univariablea		Multivariableb
		Rho	P	R2	F	P
Dependent variable: rMSSD
hs-CRP	57	− 0.420	0.001	0.334	3.036	0.088
Ln (hs-CRP)				0. 490	10.481	0.002⁎
IL-6	62	− 0.258	0.043	0.216	0.230	0.633
Ln (IL-6 + 1)				0.307	0.309	0.581
VAS	63	− 0.437	< 0.001	0.303	7.015	0.011⁎
Ln (VAS + 1)				0.384	7.045	0.010⁎
Dependent variable: pNN50
hs-CRP	57	− 0.430	0.001	0.388	3.270	0.077
Ln (hs-CRP)				0.458	10.060	0.003
VAS	63	− 0.419	0.001	0.356	7.179	0.010⁎
Ln (VAS + 1)				0.526	7.364	0.009⁎
Dependent variable: LF power
hs-CRP	57	− 0.371	0.004	0.210	1.703	0.198
Ln (hs-CRP)				0.356	5.408	0.024⁎
VAS	63	− 0.367	0.003	0.167	2.496	0.120
Ln (VAS + 1)				0.283	4.105	0.048⁎
IL-6	62	− 0.270	0.034	0.130	0.093	0.761
Ln (IL-6 + 1)				0.230	0.099	0.755
Dependent variable: HF power
hs-CRP	57	− 0.348	0.008	0.311	1.417	0.240
Ln (hs-CRP)				0.446	5.848	0.019⁎
VAS	63	− 0.371	0.003	0.209	1.928	0.171
Ln (VAS + 1)				0.313	3.043	0.087
Dependent variable: LF/HF ratio
IL-10	62	− 0.262	0.040	− 0.01	2.639	0.110
Ln (IL-10 + 1)				0.125	3.891	0.054
Dependent variable: SD1
hs-CRP	57	− 0.420	0.001	0.334	3.038	0.088
Ln (hs-CRP)				0.490	10.484	0.002⁎
IL-6	62	− 0.258	0.043	0.216	0.230	0.633
Ln (IL-6 + 1)				0.307	0.309	0.581
VAS	63	− 0.437	< 0.001	0.303	7.017	0.011⁎
Ln (VAS + 1)				0.384	7.046	0.010⁎
Dependent variable: SD2
hs-CRP	57	− 0.344	0.009	0.236	2.341	0.132
Ln (hs-CRP)				0.370	5.462	0.024⁎
IL-6	62	− 0.313	0.013	0.164	0.125	0.725
Ln (IL-6 + 1)				0.259	0.095	0.760
VAS	63	− 0.390	0.002	0.227	4.531	0.038⁎
Ln (VAS + 1)				0.317	4.625	0.036⁎

^aSpearman's rank.

^bAfter adjustment for age, sex, BMI, presence of hypertension, RA diagnosis and haemoglobin concentration.

^⁎p < 0.05