Table 3.

Association between inflammation, pain and mental stress responses before and after multivariable adjustment.

	N	Univariablea		Multivariableb
		Rho	P	R2	F	P
Dependent variable: ∆ HR PASAT
IL-10	50	0.187	0.194	0.203	5.831	0.020⁎
Ln (IL-10 + 1)				0.191	5.107	0.029⁎
VAS	50	− 0.244	0.088	0.119	1.257	0.269
Ln (VAS + 1)				0.103	0.493	0.487
Dependent variable: ∆ Mean BP PASAT
Number of tender joints	20	− 0.376	0.102	0.610	5.996	0.029⁎
Dependent variable: ∆ Systolic BP PASAT
Number of tender joints	20	− 0.403	0.078	0.529	4.455	0.055
Dependent variable: ∆ leg blood flow
hs-CRP	45	0.287	0.056	0.133	0.451	0.506
Ln (hs-CRP)				0.152	1.297	0.262
Dependent variable: ∆ LVC
hs-CRP	45	0.246	0.103	0.083	0.337	0.565
Ln (hs-CRP)				0.112	1.580	0.217
IL-6	49	0.237	0.101	0.085	0.473	0.495
Ln (IL-6 + 1)				0.108	1.545	0.221
Dependent variable: ∆ forearm blood flow
IL-10	50	0.198	0.168	0.220	5.435	0.025⁎
Ln (IL-10 + 1)				0.188	3.563	0.066
DAS28-CRPc	20	− 0.394	0.086	0.434	2.008	0.182
Tender	20	− 0.394	0.110	0.407	3.253	0.095
Dependent variable: ∆ FVC
IL-10	50	0.250	0.080	0.197	4.555	0.039⁎
Ln (IL-10 + 1)				0.190	4.151	0.048⁎
DAS28-CRPc	20	− 0.402	0.079	0.361	1.627	0.226

^aSpearman's rank.

^bAfter adjustment for age, sex, BMI, presence of hypertension, RA diagnosis and haemoglobin concentration.

^cAfter adjustment for age, sex, BMI, presence of hypertension, haemoglobin concentration and RA duration.

^⁎p < 0.05.