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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Drug Alcohol Depend. 2016 Nov 10;170:112–119. doi: 10.1016/j.drugalcdep.2016.11.002

Figure 1.

Figure 1

Effects of acute ethanol pretreatment (0.5 – 2.0 g/kg, IG) on cocaine self-administration under a second-order [FI 10 min (FR 30:S)] schedule of reinforcement. Ordinate: mean overall rate of responding (responses/second). Abscissae: unit dose of cocaine (mg/kg/injection) available for self-administration. Data represent mean ± S.D. of at least two EtOH determinations for each subject. Filled symbols indicate a statistically significant difference (P < 0.05) compared to vehicle within a given unit cocaine dose.