Table 5.

Two locus analysis. FGF2 interactions with CFH and LOC387715

	OR (95 % CI)
	rs6820411
	C/C	C/A	A/A	Interaction P
CFH
rs1329421
A/A	1	2.2 (4.6–1.1)	0 (0-NA)	0.500
A/T	2.1 (3.2–1.4)	3.7 (6.8–2)	3.3 (18.6–0.6)
T/T	3.3 (5.6–2)	12.5 (37–4.2)	NA
rs1329428
G/G	1	2.3 (4.4–1.2)	0.6 (9.2–0.04)	0.373
A/G	0.5 (0.7–0.3)	1.1 (2.2–0.6)	1.1 (6.3–0.2)
A/A	0.2 (0.34–0.1)	0.1 (0.5–0.02)	NA
rs3766404
T/T	1	1.9 (3.1–1.2)	0.7 (3.6–0.1)	0.124
C/T	0.4 (0.7–0.3)	1.1 (2.5–0.4)	NA
C/C	0.2 (0.7–0.05)	NA	NA
rs1831282
T/T	1	2.1 (4.4–1)	NA	0.729
C/T	2 (3–1.33)	3.8 (7.1–2.1)	2.2 (10.2–0.5)
C/C	3.3 (5.5–2)	10.3 (28–3.8)	NA
rs12144939
G/G	1	2.3 (3.9–1.4)	1.1 (6.4–.2)	0.836
G/T	0.5(0.7–0.3)	1.1 (2.3–0.5)	1.4 (15.6–0.1)
T/T	0.1 (0.5–0.04)	0.1 (1.2–0.02)	NA
LOC387715
rs10490924
G/G	1	2.5 (4.5–1.4)	2.1 (10.9–0.5)	0.858
G/T	4.1 (6.2–2.7)	8.7 (17–4.5)	NA
T/T	14.5 (31.9–6.6)	16.1 (72.1–3.6)	NA