Fig. 1.

(a) Laser speckle imaging set-up. The laser projects a diffuse speckle pattern onto the sample which is imaged using a CMOS camera. (b) Sample geometry for validation experiments (experimental and computational). The sample consisted of a variable thickness (0.75-4.0mm) top layer above a 5cm bottom layer. For experiments with flow present, a glass microchannel inclusion was placed at the surface of the second layer and Intralipid infused through the tube with a syringe pump. (c) Results from simulated flow in a subsurface inclusion. We modeled speckle contrast for flow through the inclusion at different speeds and exposure times. As expected, speckle contrast decreased with increasing flow speed and exposure time. The results closely matched previous work by Rice et al [41].