Figure S6.

CRAC Crosslinks and Crystal Structures, Related to Figure 2

(A) CRAC analysis hits of yeast Brx1 (blue, top plot) and untagged wild-type strain (red, top plot) as well as Rpf1 (black, bottom plot) and untagged wild-type strain (green, bottom plot). A schematic representation of the 35S pre-rRNA is drawn below the x axis. The number of hits per 1000 total mapped reads is plotted against the nucleotide position on the rDNA.

(B) Comparison of the cryo-EM model (top) of Nsa1 with its crystal structure (bottom).

(C) Comparison of the cryo-EM model (top) of Rrp1 with the crystal structure of Chaetomium thermophilum Rrp1 (bottom).