Effects of PPC on brain water content (BWC) and neurobehavioral performance at 24h and 72h post SBI. (A and B) PPC+SBI group had significantly decreased BWC in the right frontal lobe compared to SPC+SBI group at 24h and 72h post surgery. (C and D) Modified Garcia score was increased significantly in PPC+SBI group compared to SPC+SBI at 24h and 72h after SBI. (E and F). Beam balance score showed no significant differences between PPC+SBI and SPC+SBI groups. Data are expressed as mean±SEM. n=6/group. ANOVA, SNK. *P<0.05 vs Sham; Δp<0.05 vs SPC+SBI; RF=Right frontal lobe, LF=Left frontal lobe, RP=Right parietal lobe, LP=Left parietal lobe, C=cerebellum, BS= Brainstem.