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PNSECM promotes migration of both M1 (CD68+CCR7+) and M2 (CD68+CD206+) macrophage phenotypes, relative to the original site of transection (A,B); an increased M2:M1 ratio (C) and increased extension of Schwann cells populations relative to the original site of transection (D). Data shown are least square (adjusted) mean and standard error (A,B,D) and mean and standard error (C). n= 3 slides/ label/animal and 7 animals /group.
