. Author manuscript; available in PMC: 2019 Mar 1.

Published in final edited form as: Abdom Radiol (NY). 2018 Mar;43(3):629–638. doi: 10.1007/s00261-017-1236-y

Table 1.

Selection criteria used in this study to select ADPKD patients and controls.

Inclusion	Exclusion
Male/female between 18 and 30 years of age, inclusive Must have a Glomerular Filtration Rate (GFR) of ≥60 mL/min (CKD-EPI equation). Ability to provide written, informed consent prior to initiation of any study-related procedures, and ability, in the opinion of the principle investigator, to comply with all requirements of the study. ADPKD patient group only: Diagnosis of ADPKD [Diagnosis for this population is based on Ravine et al. and requires several cysts in each kidney (3 if by sonography, 5 if by computed topography (CT) or MRI in those with a family history of ADPKD and 10 cysts (by radiologic method) in each kidney and exclusion of other cystic kidney diseases if there is no family history]	Clinically significant concomitant systemic disease investigator’s opinion may place the subject at risk affect the kidney. This includes, but is not limited history of lupus, hepatitis B or C, amyloidosis, etc. Subjects with diabetes mellitus (fasting glucose treatment with insulin or oral hypoglycemics). Urinary protein excretion Abnormal urinalysis suggestive of concomitant Subjects having contraindications to, or interference assessments. [e.g. ferromagnetic metal prostheses, clips, severe claustrophobia, large abdominal/back Subjects with supine blood pressure, after resting >140/90 mm Hg or are taking blood pressure medications. Female subjects that are pregnant Control group only: Previous personal or family history of kidney disease

Inclusion

Exclusion

Male/female between 18 and 30 years of age, inclusive

Must have a Glomerular Filtration Rate (GFR) of ≥60 mL/min (CKD-EPI equation).

Ability to provide written, informed consent prior to initiation of any study-related procedures, and ability, in the opinion of the principle investigator, to comply with all requirements of the study.

ADPKD patient group only:
Diagnosis of ADPKD [Diagnosis for this population is based on Ravine et al. and requires several cysts in each kidney (3 if by sonography, 5 if by computed topography (CT) or MRI in those with a family history of ADPKD and 10 cysts (by radiologic method) in each kidney and exclusion of other cystic kidney diseases if there is no family history]

Clinically significant concomitant systemic disease investigator’s opinion may place the subject at risk affect the kidney. This includes, but is not limited history of lupus, hepatitis B or C, amyloidosis, etc.

Subjects with diabetes mellitus (fasting glucose treatment with insulin or oral hypoglycemics).

Urinary protein excretion

Abnormal urinalysis suggestive of concomitant

Subjects having contraindications to, or interference assessments. [e.g. ferromagnetic metal prostheses, clips, severe claustrophobia, large abdominal/back

Subjects with supine blood pressure, after resting >140/90 mm Hg or are taking blood pressure medications.

Female subjects that are pregnant

Control group only:
Previous personal or family history of kidney disease