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. 2017 Dec 13;6(4):37. doi: 10.3390/antibiotics6040037

Table 1.

Antifungal activity of stem wood and bark extracts of T. brownii. Results were obtained using cup well agar diffusion and agar dilution methods.

Fungal Strain Stem Wood Extracts Stem Bark Extracts Amphotericin-B
IZ MIC IZ MIC IZ MIC
Aspergillus niger
Pt NA NA
CHCl3 12 ± 0.9 13 ± 0.4
EtOAc 17± 0.7 500 17 ± 0.8 500 35 ± 0.01 31.25
aqueous 17± 0.5 16.5 ± 0.4
Aspergillus flavus
Pt NA NA
CHCl3 14 ± 0.5 14 ± 0.9
EtOAc 18.5 ± 0.4 500 18.5 ± 0.8 500 28 ± 0.03 125
aqueous 18 ± 0.9 18 ± 0.5
Nattrassia mangiferae
Pt NA NA
CHCl3 12 ± 0.5 12± 0.7
EtOAc 19 ± 0.4 250 18.5 ± 0.4 250 30 ± 0.04 62.5
aqueous 18.5 ± 0.4 19 ± 0.4
Fusarium verticillioides
Pt NA NA
CHCl3 13 ± 0.6 11 ± 0.9
EtOAc 20 ± 0.4 250 19 ± 0.2 250 31 ± 0.03 62.5
aqueous 19 ± 0.3 18 ± 0.7

For agar diffusion, extracts at the concentration 1 mg/mL were used. Diameter of inhibition zones (IZ) in mm: >18 mm: sensitive; 14–18 mm: intermediate; <14 mm: resistant [55,56]; Pt, petroleum ether extracts; CHCL3, chloroform extracts; EtOAc, ethyl acetate extracts; NA, Not active. IZ results as mean ± SEM of five measurements. MIC in µg/mL. The observed differences between the sample means of the inhibition zones (the stem bark and wood extracts) against the tested fungi did not differ significantly.