Figure 2.

MnP treatment reduces weight gain in high fat diet (HFD)-fed mice. Over 12 weeks of HFD feeding, weights were recorded for Lean (empty squares, solid line), HFD (filled squares, solid line), and HFD + MnP (filled squares, dashed line) mice, n = 5 mice per group. Data is displayed as mean ± SEM. Significance was calculated by two-way ANOVA with a Tukey post-test of multiple comparisons. Significant differences were observed between Lean and HFD starting at 3 weeks (#), between HFD and HFD + MnP starting at 4 weeks (*), and between Lean and HFD + MnP starting at 7 weeks (†), all lasting the duration of the experiment.