Table 2.
Percentage of changes in day wheeze (DW), exercise wheeze (EW), FEV1, and NO2- at time I relative to time O (I/O), time II relative to time O (II/O) and, time II relative to time I (II/I) in treated groups
| Time | Group | DW | EW | FEV 1 | NO 2- |
|---|---|---|---|---|---|
| I/O | P | -25±35.36 -53.33±50.18 -66.67±37.68* -51.67±47.43 |
100±0.00 -36.67±20.49*** -26.67±23.83*** -53.33±37.52*** |
-6.05 ±12.51 7.9±7.16 ** 9.84±19.68* 15.17±15.74*** |
14.05±64.02 -4.33±37.79 -4.23±8.91 -6.39±12.64 |
| Z low | |||||
| Z high | |||||
| C | |||||
| II/O | P | -10±31.62 -63.33±48.30* -70.00±35.83** -61.67±45.85* |
100 ±0.00 -43.33±23.83*** + -31.67±22.84***++ -73.33±28.54*** |
-12.98±19.81 8.91±6.36** 12.28±9.88*** 19.21±16.49*** |
-3.80±28.72 -5.59±37.03 -16.77±12.85 -29.46±18.19* |
| Z low | |||||
| Z high | |||||
| C | |||||
| II/I | P | 20±63.25 -10.00±31.62 -5.00±15.81 -15.00±33.75 |
0.00±0.00 -10±21.08 -30±34.96 -25±42.49 |
-6.47±17.39 1.01±3.17 3.72±11.7 3.56±4.91 |
-6.65±20.18 -1.33±11.59++ -13.15±9.61 -23.95±20.34 |
| Z low | |||||
| Z high | |||||
| C |
The results are presented as mean ± SD. Statistical comparisons were performed using independent T-test.
P: Placebo group; Z low group were treated with 5 mg/kg/day of the extract; Z high group were treated with 10 mg/kg/day of the extract; C group were treated with 1.2 mg/kg/day carvacrol.
*
p<0.05,
**
p<0.01, and
***
p<0.001, show significant differences as compared to group P.
+
p<0.05, and
++
p<0.01, show significant differences as compared to group C