Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jan;188(1):84–94. doi: 10.1016/j.ajpath.2017.09.015

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2018 American Society for Investigative Pathology. Published by Elsevier Inc. All rights reserved.

This document may be redistributed and reused, subject to certain conditions.

PMC Copyright notice

Supplemental Figure S4 — Ectopic Sox9 expression in proximal tubular–derived cystic segments with decreased lotus tetragonolobus lectin (LTL) staining in adult Ift88 knock-out (KO) kidneys 3 weeks after ischemia-reperfusion (IR).Representative co-immunofluorescence images for Sox9 (red) and LTL (green) in control and Ift88KO, 3 weeks after IR injury or sham surgery. A and B: No Sox9 signal is present. LTL-positive cells in control kidneys subjected to sham surgery (A, arrowhead) or to IR injury (B, arrowhead). C: In Ift88KO kidneys subjected to sham surgery, no Sox9 signal is observed in LTL-positive proximal tubules (arrowhead). D: In Ift88KO/IR kidneys, Sox9 is absent in LTL-positive tubules and cystic cells (arrowhead), but is expressed ectopically in cystic segments with reduced LTL staining (concave arrowheads). Scale bar = 50 μm.