Table 2.

Relative Role of P2Y₂ Receptor on Tyrosine Phosphorylation

Sequence	Modifications	Ratio H/L
EGFR	p-Tyr-974	0.345
	p-Tyr-1086	0.230
	p-Tyr-1148	0.779
	p-Tyr-1173	1.215
Src	p-Tyr-421	0.339
	p-Tyr-446	0.128
SHC	p-Tyr-42	0.694
MAPK-1	p-Tyr-187	0.789
Paxillin	p-Tyr-118	0.100

Subset of SILAC-based quantitative phosphorylation profile from cells transfected with siRNA to P2Y₂ receptor and stimulated with UTP (H) compared with cells transfected with siRNA to nontargeting sequence (L) (see Figure 6). Phosphorylation is presented as the ratio of H/L.