Table 2.
Univariate and Multivariate Analyses of Factors Predictive of Invasive Cancer or High-Grade Dysplasia in Pancreatic Cysts
| Variables | LGD IGD | HGD INV | Univariate P | Multivariate |
||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | ||||
| Age | ||||||
| <65 years | 16 | 9 | 0.167 | |||
| ≥65 years | 32 | 36 | ||||
| Sex | ||||||
| Female | 27 | 18 | 0.148 | |||
| Male | 21 | 27 | ||||
| Fluid appearance | ||||||
| Serous | 37 | 20 | 0.002∗ | 1.000 | ||
| Mucinous | 11 | 25 | 2.671 | 0.871–8.473 | 0.086 | |
| Cyst size | ||||||
| <30 mm | 29 | 21 | 0.215 | |||
| ≥30 mm | 19 | 24 | ||||
| MPD dilatation | ||||||
| <5 mm | 40 | 13 | <0.001∗ | 1.000 | ||
| ≥5 mm | 8 | 32 | 12.924 | 4.207–46.000 | <0.001∗ | |
| Mural nodule/solid component | ||||||
| Absent | 36 | 27 | 0.183∗ | |||
| Present | 12 | 18 | ||||
| Clinical symptoms | ||||||
| Absent | 39 | 20 | <0.001 | 1.000 | ||
| Present | 9 | 25 | 4.019 | 1.272–13.878 | 0.018∗ | |
| Telomere fusion | ||||||
| Negative | 42 | 30 | 0.025∗ | 1.000 | ||
| Positive | 6 | 15 | 6.229 | 1.605–27.988 | 0.008∗ | |
HGD, high-grade dysplasia; IGD, intermediate-grade dysplasia; INV, invasive cancer; LGD, low-grade dysplasia; MPD, main pancreatic duct; OR, odds ratio.
∗
Statistically significant.