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. 2017 Oct 16;7(4):38. doi: 10.3390/life7040038

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The effect of the distributions of ribozyme self-assembly rates on cooperation. (a) Flat random vs. real rate constants. The Empirically derived rate constants show an enhanced level of cooperative relative to a completely randomized control. (b) Log random vs. real rate constants. The empirically derived distribution of cooperation is well explained by a logarithmically distributed random distribution. (c) WC pairs vs. real. The empirically derived distribution of cooperation is not completely explained by including two values of rate constants. (d) WC with three wobble pairs vs. real. The empirically derived rate distribution of cooperation is well explained by including wobble pairs in a simplified set of rate constants.