Table 5.

Univariate and multivariate analyses of progression-free survival and overall survival

Univariate analysis
	No. of patients	Median PFS (months, 95% CI)	p-value	Median OS (months, 95% CI)	p-value
LN SUVmax decrease
< 73%	20	17.1 (6.8–27.4)	0.021	25.4 (11.5–39.3)	0.006
≥ 73%	23	NA		NA
Total MTV decrease
< 78%	8	8.7 (6.7–10.7)	<0.001	16.6 (8.9–24.4)	<0.001
≥ 78%	35	NA		NA
Multivariate analysis
		HR	95% CI	p-value
PFS
Total MTV decrease ≥78%		7.5	2.7–20.9	<0.001
LN SUVmax decrease ≥73%		3.0	1.1–8.0	0.028
OS
Total MTV decrease ≥78%		17.0	5.0–57.4	<0.001
LN SUVmax decrease ≥73%		5.2	1.4–19.0	0.006

SUVmax maximum standardized uptake value, MTV metabolic tumor volume, PFS progression-free survival, OS overall survival, HR hazard ratio, CI confidence interval