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. 2017 Dec 28;17:901. doi: 10.1186/s12885-017-3728-0

Table 4.

Association with the occurrence of CRC (univariate conditional logistic regression) for genetic covariates

Gene Variant Model Univariate
HR 95% CI p-value
UGT1A6 rs1105879 C vs. A 1.05 0.82 1.35 0.687
UGT1A7 rs11692021 T vs. C 0.97 0.76 1.24 0.817
UGT1A9 rs2741045 T vs. C 1.00 0.77 1.29 0.970
UGT2B7 rs7438135 G vs. A 1.12 0.89 1.40 0.348
ABCB1 rs1128503 T vs. C 0.99 0.78 1.25 0.910
rs2032582 T vs. G 0.96 0.76 1.21 0.727
rs1045642 T vs. C 1.05 0.84 1.32 0.683
Haplotype TTT/other vs. Other/other 1.02 0.72–1.45 0.898
TTT/TTT vs. Other/other 0.98 0.59–1.65 0.949
ABCC2 rs717620 T vs. C 0.98 0.74 1.28 0.864
rs2273697 G vs. A 1.03 0.77 1.36 0.853
rs3740066 T vs. C 1.02 0.81 1.29 0.847
SLCO1B1 rs4149056 T vs. C 0.82 0.59 1.12 0.213
rs2306283 G vs. A 1.03 0.83 1.29 0.770
SLCO2B1 rs2306168 CC vs CT 1 0.41–2.43 0.994
rs12422149 AA vs AG 1.02 0.68 1.52 0.932