Table 9.
GO and KEGG enrichment results for the 29 predicted and anticorrelated mRNAs targets of five miRNAs differentially expressed in the chronic period
| GO terms | Term description | GO ID | Size of term | miRNA target | Expected | Enrichment ratio | Raw p value | FDR |
|---|---|---|---|---|---|---|---|---|
| Biological process | Negative regulation of DC differentiation | GO:2001198 | C = 2 | O = 2 | E = 0 | R = 576.79 | 2.88E-06 | 0.0005 |
| Biological process | Regulation of DC differentiation | GO:2001199 | C = 2 | O = 2 | E = 0 | R = 576.79 | 2.88E-06 | 0.0005 |
| Biological process | DC differentiation | GO:0097028 | C = 13 | O = 2 | E = 0.02 | R = 88.74 | 0.0002 | 0.0178 |
| Biological process | Glial cell development | GO:0021782 | C = 69 | O = 3 | E = 0.12 | R = 25.08 | 0.0002 | 0.0178 |
| Biological process | Regulation of glial cell proliferation | GO:0060251 | C = 16 | O = 2 | E = 0.03 | R = 72.10 | 0.0003 | 0.0214 |
| Biological process | Glial cell proliferation | GO:0014009 | C = 23 | O = 2 | E = 0.04 | R = 50.16 | 0.0007 | 0.0356 |
| Biological process | Regulation of immune system process | GO:0002682 | C = 653 | O = 6 | E = 1.13 | R = 5.30 | 0.0007 | 0.0356 |
| Biological process | Response to wounding | GO:0009611 | C = 692 | O = 6 | E = 1.20 | R = 5 | 0.0009 | 0.0401 |
| Biological process | Negative regulation of DNA binding | GO:0043392 | C = 31 | O = 2 | E = 0.05 | R = 37.21 | 0.0013 | 0.0498 |
| Biological process | Oligodendrocyte development | GO:0014003 | C = 32 | O = 2 | E = 0.06 | R = 36.05 | 0.0014 | 0.0498 |
| KEGG pathway | Hematopoietic cell lineage | C = 124 | O = 3 | E = 0.07 | R = 40.29 | 5.70E-05 | 0.001 | |
| KEGG pathway | Lysosome | C = 79 | O = 2 | E = 0.05 | R = 42.16 | 0.001 | 0.0015 |