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. 2017 Dec 28;14:79. doi: 10.1186/s12986-017-0234-y

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© The Author(s). 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — The experimental groups. Group I represents the adipogenic group, when the cells reached 100% confluence after 2 days (set for 0 days, D0), and the replacement of the adipogenic inducers (based on the growth medium, insulin, dexamethasone and 3-isobutyl-1-methylxanthine) was added to induce the adipogenic differentiation of 3 T3-L1 preadipocytes for 2 days, after 14 days (D14) of continuous induction. In addition, the I + AA2P group, the I + EDHB group the I + U0126 group were added to AA2P, EDHB and U0126 based on the I group at D0, and were continuously induced for 14 days (D14). N.I. represents the non-induced group; the Lenti-Col VI-GFP represents the Col VI knockdown group that used RNAi