Table 1.
Number | Experimental group | Treatment |
---|---|---|
(1) | Control | Standard diet (Laboratory Rodent Diet 5001) ad libitum |
(2) | Hypercholesterolemia | Hypercholesterolemic diet (1% cholesterol, 0.5% cholic acid) ad libitum |
(3) | Ezetimibe | Ezetimibe 10 mg/kg and hypercholesterolemic diet ad libitum (Merck/Schering-Plough Pharmaceuticals, USA) |
(4) | Hydroalcoholic extract | Extract of Eryngium carlinae at a dose of 100 mg/kg and hypercholesterolemic diet and water ad libitum |
(5) | Hydroalcoholic extract | Extract of Eryngium carlinae at a dose of 500 mg/kg and hypercholesterolemic diet ad libitum |
(6) | Hexa-O-acetyl-D-mannitol | Mannitol hexaacetate at a dose of 10 mg/kg and hypercholesterolemic diet ad libitum |
(7) | D-Mannitol | D-Mannitol at a dose of 10 mg/kg and hypercholesterolemic diet ad libitum |
Different treatments during the evaluation of Eryngium carlinae. All treatments were administered every day at 15:00 h for four weeks.