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. 2017 Dec 28;17:124. doi: 10.1186/s12935-017-0495-6

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© The Author(s) 2017

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Effect of matrine and cisplatin alone and in combination on cell cycle arrest. The percentage of cells in G1, S or G2/M phase in EJ (a) or T24 cells (b) treated with 5 mM of matrine, 4 μM of cisplatin alone and 1 μM of cisplatin and 2 mM of matrine in combination for 48 h. Data represent the cell population of cell cycle arrest of EJ (c) and T24 (d). All data are shown as the mean ± SD of three independent experiments. *P < 0.05, **P < 0.01, ***P < 0.001, or ****P < 0.0001 versus the control group