Table 3.
Blood lactate concentration of mice exposed to fine particulate matter (PM2.5) submitted to exercise training.
CON | PM2.5 | MIT | MIT + PM2.5 | HIT | HIT + PM2.5 | ANOVA (P value) | |
---|---|---|---|---|---|---|---|
5th week | — | — | 4.54 ± 0.21 | 3.90 ± 0.33 | 4.17 ± 0.22 | 4.04 ± 0.19 | 0.299 |
9th week | — | — | 4.20 ± 0.20 | 4.00 ± 0.20 | 5.13 ± 0.86∗ | 5.40 ± 0.36∗ | 0.024∗ |
Blood lactate concentration (mmol·L−1) expressed as mean ± SEM. CON: control group, received 10 μL saline daily, maintained sedentary. MIT: moderate intensity training group, received 10 μL saline daily. HIT: high intensity training group, received 10 μL saline daily. PM2.5: exposure group, received 5 μg of PM2.5 daily, maintained sedentary. MIT + PM2.5: moderate intensity training group, received 5 μg of PM2.5 daily. HIT + PM2.5: high intensity training group, received 5 μg of PM2.5 daily (n = 5-6 per group). Data analysed by two-way ANOVA followed by Tukey's multiple comparison test. There was no effect of PM2.5 (P < 0.940) and interaction (P = 0.617), but there was an effect of exercise (P = 0.033). Both HIT and HIT + PM2.5 showed higher levels in the 8th week in comparison with the MIT and MIT + PM2.5 groups (∗P = 0.024) and also higher than itself in the 5th week of exercise effort (∗P = 0.039).