Table 5.
Haematological parameters of mice exposed to fine particulate matter (PM2.5) submitted to 12 weeks of exercise training.
| CON | PM2.5 | MIT | MIT + PM2.5 | HIT | HIT + PM2.5 | ANOVA (P value) | |
|---|---|---|---|---|---|---|---|
| WBC (103·mm−3) | 10.8 ± 2.8 | 6.8 ± 3.1 | 8.9 ± 3.3 | 7.2 ± 3.1 | 7.6 ± 1.2 | 6.6 ± 0.8 | 0.146 |
| LYM 103·mm−3 (%LYM) | 8.96 ± 2.38 (83.0 ± 4.4) | 5.86 ± 2.87 (84.5 ± 1.5) | 7.56 ± 3.13 (83.4 ± 3.2) | 6.85 ± 2.68 (82.3 ± 2.4) | 6.51 ± 0.93 (84.5 ± 4.5) | 5.46 ± 0.81 (82.0 ± 3.0) | 0.214 |
| MON 103·mm−3 (%MON) | 0.58 ± 0.19 (5.3 ± 0.8) | 0.31 ± 0.14∗ (5.0 ± 0.9) | 0.43 ± 0.12 (5.0 ± 1.2) | 0.47 ± 0.17 (5.1 ± 0.8) | 0.37 ± 0.06 (5.2 ± 0.9) | 0.35 ± 0.06 (5.1 ± 0.8) | 0.041∗ |
| GRA 103·mm−3 (%GRA) | 1.34 ± 0.56 (12.5 ± 3.8) | 0.63 ± 0.31∗ (9.6 ± 2.8) | 0.97 ± 0.19 (11.6 ± 3.2) | 0.99 ± 0.30 (12.5 ± 2.5) | 0.71 ± 0.50 (10.2 ± 4.9) | 0.87 ± 0.15 (13.2 ± 3.1) | 0.047∗ |
| RBC (106·mm−3) | 10.5 ± 1.1 | 7.92 ± 0.4 | 9.7 ± 1.3 | 8.94 ± 0.9 | 7.8 ± 1.7 | 8.31 ± 0.6 | 0.220 |
| HGB (g·dL−1) | 17.4 ± 3.9 | 13.6 ± 1.5 | 15.8 ± 4.0 | 14.6 ± 2.9 | 13.3 ± 5.1 | 13.2 ± 2.2 | 0.286 |
| HCT (%) | 40.2 ± 1.5 | 34.5 ± 1.5 | 39.8 ± 1.5 | 40.6 ± 4.5 | 37.1 ± 1.6 | 37.6 ± 2.9 | 0.291 |
| PLT (103·mm−3) | 1436 ± 329 | 975 ± 372 | 1124 ± 364 | 1157 ± 248 | 1036 ± 575 | 906 ± 145 | 0.210 |
| NEU/LYM ratio (103·mm−3) | 0.15 ± 0.05 | 0.11 ± 0.03 | 0.14 ± 0.04 | 0.15 ± 0.03 | 0.10 ± 0.06 | 0.16 ± 0.04 | 0.425 |
Haematological parameters expressed as mean ± SEM. CON: control group, received 10 μL saline daily, maintained sedentary. MIT: moderate intensity training group, received 10 μL saline daily. HIT: high intensity training group, received 10 μL saline daily. PM2.5: EXPOSURE group, received 5 μg of PM2.5 daily, maintained sedentary. MIT + PM2.5: moderate intensity training group, received 5 μg of PM2.5 daily. HIT + PM2.5: high intensity training group, received 5 μg of PM2.5 daily (n = 5-6 per group). Data analysed by two-way ANOVA followed by Tukey's post hoc test. P values describe here in each variable in terms of the PM2.5 effect, exercise effect, and interaction, respectively. WBC: white blood cell (P = 0.291, P = 0.139, and P = 0.106). %LYM: lymphocyte percentage (P = 0.629, P = 0.548, and P = 0.214). %MON = monocyte percentage (P = 0.680, P = 0.575, and P = 0.220). %GRA: granulocyte percentage (P = 0.910, P = 0.985, and P = 0.761). RBC: red blood cells (P = 0.567, P = 0.783, and P = 0.741). HGB: haemoglobin (P = 0.118, P = 0.777, and P = 0.931). HCT: haematocrit (P = 0.438, P = 0.367, and P = 0.291). PLT: platelet total count (P = 0.0810, P = 0.335, and P = 0.224). ∗P < 0.05 versus the control group; one-way ANOVA.