Table 2.
Correlation between clinico-pathological features and the expressions of EMMPRIN in NSCLC tissues (n=55)
| Items | Groups | N | Expressions of EMMPRIN in lung tissues | |||
|---|---|---|---|---|---|---|
| Negative (%) | Positive (%) | χ2 value | P value | |||
| Resourse | ||||||
| Normal | 55 | 41(74.5) | 14(25.5) | 8.591 | 0.003 | |
| NSCLC | 55 | 26(47.3) | 29(52.7) | |||
| Gender | ||||||
| Male | 36 | 19(52.8) | 17(47.2) | 1.267 | 0.260 | |
| Female | 19 | 7(36.8) | 12(63.2) | |||
| Ages | ||||||
| <60 | 27 | 13(48.1) | 14(51.9) | 0.016 | 0.898 | |
| ≥60 | 28 | 13(46.4) | 15(53.6) | |||
| Smoking | ||||||
| Yes | 21 | 13(61.9) | 8(38.1) | 2.918 | 0.088 | |
| No | 34 | 13(38.2) | 21(61.8) | |||
| Histology | ||||||
| LAC | 23 | 7(30.4) | 16(69.6) | 4.496 | 0.034 | |
| LSCC | 32 | 19(59.4) | 13(40.6) | |||
| Pathological grade | ||||||
| Poorly | 17 | 2(11.8) | 15(88.2) | 20.762 | <0.001 | |
| Moderately | 13 | 4(30.8) | 9(69.2) | |||
| Well | 25 | 20(80) | 5(20) | |||
| Lymphatic invasion | ||||||
| N0 - N1 | 26 | 20(76.9) | 6(23.1) | 17.392 | <0.001 | |
| N2 - N3 | 29 | 6(20.7) | 23(79.3) | |||
| pTNM | ||||||
| IIA-IIIA | 35 | 24(68.6) | 11(31.4) | 17.517 | <0.001 | |
| IIIB | 20 | 2(10) | 18(90) | |||
LAC, lung adenocarcinoma; LSCC, lung squamous cell carcinoma; Smoking, pack years of smoking; T stage, tumor size; pTNM, clinical stage of lung cancer