Skip to main content
. Author manuscript; available in PMC: 2018 Jan 10.
Published in final edited form as: Biochemistry. 2016 Dec 27;56(1):324–333. doi: 10.1021/acs.biochem.6b01107

Figure 1. Inhibition of chymotryptic activities of Mtb20SOG and the human c-20S and i-20S by N,C-capped dipeptides.

Figure 1

(A) The four sub-site positions of a 20S CP surrounding a dipeptide inhibitor. (B) Structures of the six dipeptide inhibitors studied in this work. (C) Dose-dependent inhibition curves for Mtb20SOG, human c-20S, and human i-20S. Each curve is a representative of three independent experiments for each compound; each data point is an average of three replicates in those experiments.