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. 2017 Nov;12(11):1885–1894. doi: 10.4103/1673-5374.219051

Figure 2.

Figure 2

Immunohistochemical images of the four subsets of microglia/macrophages being investigated in thoracic spinal cord injury rats.

(A) IBA1+/ED1 ramified microglia: long and thin processes extending to the parenchyma with a small cell soma (asterisk). (B) IBA1+/ED1 activated microglia: exhibit two morphological appearances; short and thicker processes with a large cell soma (arrow head) or amoeboid-like appearance (open arrow head). (C) IBA1+/ED1+ activated microglia/macrophage: amoeboid-like appearance with very few, if any, processes (arrow). (D) IBA1/ED1+ macrophages: amoeboid appearance with a large cell soma (open arrow). Scale bars: 10 μm.