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PAH-targeted therapy received prior to switching to riociguat
| Therapy, n (%) | Full analysis set (n = 300) |
|---|---|
| Any prior therapy | 84 (28) |
| Endothelin receptor antagonists | 44 (15) |
| Ambrisentan | 8 (3) |
| Bosentan | 36 (12) |
| PDE5 inhibitors | 58 (19) |
| Sildenafil | 42 (14) |
| Tadalafil | 16 (5) |
| Prostacyclins and prostacyclin analogues | 7 (2) |
| Beraprost | 1 (<1) |
| Iloprost | 6 (2) |
| Combination therapy | 24 (8) |
| Double therapy | 23 (8) |
| Triple therapy | 1 (<1) |
PAH pulmonary arterial hypertension, PDE5 phosphodiesterase type 5
