Table 10.

Comparison of work productivity and activity impairment questionnaire at baseline between dry eye disease and control populations (all enrolled population)

Question	All cases (n = 217)	All controls (n = 67)	P-value
Currently employed, n (%)
Yes	100 (46.76%)	40 (59.70%)	0.0699
No	114 (53.27%)	27 (40.30%)
Hours missed work due to health
N	106	42
Mean (SD)	0.48 (2.846)	0.19 (1.234)	0.5248
Min–Max	0–25	0–8
Hours missed work due to other reasons
N	106	42
Mean (SD)	2.02 (5.174)	2.30 (6.098)	0.7776
Min–Max	0–40	0–30
Hours actually worked
N	109	42
Mean (SD)	30.87 (16.202)	31.04 (17.603)	0.9554
Min–Max	0–62	0–60
Productivity affected by health problems
N	108	42
Mean (SD)	1.63 (2.538)	0.17 (0.660)	0.0003
Min–Max	0–10	0–3
Regular activities affected by health problems
N	200	66
Mean (SD)	1.83 (2.280)	0.59 (1.617)	<0.0001
Min–Max	0–10	0–9

Health problem productivity was evaluated by the patient using an 11-point scale where 0 = no effect and 10 = completely prevented me from working. Health problem activities were evaluated by the patient using an 11 point scale where 0 = no effect and 10 = completely prevented me from doing my daily activities

P-values for continuous endpoints taken from two sample t-tests

P-values from categorical endpoints taken from chi-squared test