Table 4.

Measures of signs and symptoms at baseline in dry eye disease and control populations (all enrolled population)

	All cases (n = 217)	All controls (n = 67)	P-value
OSDI Score
Mean (SD)	31.7 (19.6)	4.1 (7.4)	<0.0001
Min-Max	0.0–91.7	0.0–39.6
Schirmer’s score (mm)
Mean (SD)	5.7 (4.2)	15.3 (7.7)	<0.0001
Min-Max	0.0–30.0	1.0–35.0
Corneal staining score
Mean (SD)	1.4 (0.9)	0.2 (0.5)	<0.0001
Min-Max	0.0–4.0	0.0–2.0
Conjunctival staining score
Mean (SD)	1.4 (1.0)	0.3 (0.6)	<0.0001
Min-Max	0.0–5.0	0.0–2.5
Tear break-up time(s)
Mean (SD)	5.7 (4.0)	8.5 (5.0)	<0.0001
Min-Max	1.0–28.3	1.3–25.0