Table 1. Correlation between YAP1 mRNA expression and clinicopathological factors of GC in the Kyushu dataset.
| Factors | Low (n = 35) Number (%) | High (n = 66) Number (%) | P-value |
|---|---|---|---|
| Age (years) | |||
| <65 | 16 (45.7) | 31 (47.0) | 0.904 |
| ≥65 | 19 (54.3) | 35 (53.0) | |
| Sex | |||
| Male | 25 (71.4) | 43 (65.1) | 0.522 |
| Female | 10 (28.6) | 23 (34.9) | |
| Histology | |||
| well/moderate | 25 (71.4) | 29 (43.9) | 0.008* |
| poorly | 10 (28.6) | 37 (56.1) | |
| Depth of invasion | |||
| ≤SM | 13 (37.1) | 12 (18.2) | 0.036* |
| ≥MP | 22 (62.9) | 54 (81.8) | |
| Lymph node metastasis | |||
| Absent | 14 (40.0) | 23 (34.9) | 0.609 |
| Present | 21 (60.0) | 43 (65.1) | |
| Lymphatic invasion | |||
| Absent | 17 (48.6) | 22 (33.3) | 0.134 |
| Present | 18 (51.4) | 44 (66.7) | |
| Venous invasion | |||
| Absent | 30 (85.7) | 43 (65.1) | 0.028* |
| Present | 5 (14.3) | 23 (34.9) | |
| Peritoneal metastasis | |||
| Absent | 31 (88.6) | 56 (84.8) | 0.606 |
| Present | 4 (11.4) | 10 (15.2) | |
| Liver metastasis | |||
| Absent | 33 (94.3) | 61 (92.4) | 0.726 |
| Present | 2 (5.7) | 5 (7.6) | |
| UICC TNM Stage | |||
| I, II | 22 (62.9) | 36 (54.6) | 0.421 |
| III, IV | 13 (37.1) | 30 (45.4) |
SM: submucosa.
MP: muscularis propria.
UICC: Union for International Cancer Control.
TNM: tumor/node/metastasis.
*P < 0.05.