Table 3. Analysis of genotypic association of rs9943582 with ischemic stroke in Chinese Han GeneID population under different genetic models of inheritance.
Cohorts | Model | P_obs* | OR (95% CI) | P_adj† | OR (95% CI) |
---|---|---|---|---|---|
Entire cohort (1,158/1,265) | Dominant | 0.89 | 1.01 (0.86–1.19) | 0.60 | 1.05 (0.89–1.24) |
Recessive | 0.28 | 1.18 (0.88–1.59) | 0.59 | 0.91 (0.87–1.24) | |
Additive | 0.54 | n.a | 0.87 | 1.01 (0.89–1.15) |
* Uncorrected P value and odds ratio (OR) using Chi-square tests with Pearson's 2 × 2.
†Adjusted P value by multivariate logistic regression analysis for potential confounders including age, gender, smoking, hypertension, diabetes mellitus and lipid concentrations (Tch, TG, HDL-c and LDL-c).
n.a.: no data.