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. 2017 Nov 11;8(64):107886–107898. doi: 10.18632/oncotarget.22386

Figure 4. miR-223 involvement in tumor cell growth, migration and invasion.

Figure 4

SUPT-1 cells that express low levels of miR-223 were transiently transfected with miR-223 precursor (mimic) or its negative control (NC) and used to analyze clonogenicity (A) or migration and invasion (B). Conversely, Jurkat cells, that expresses high level of miR-223, were transiently transfected with inhibitor (anti-miR or anti-control) and used to analyze clonogenicity (C) or migration and invasion (D). The results are shown as number of colonies measured at 10 days by colony assay (A-C), and percentage (%) of migration and invasion by Transwell-migrating or Matrigel-invading cells (B-D). Clonogenicity, migration and invasion of miR-modulated cells are shown relative to negative control values. Two or three independent experiments were performed in triplicate and mean results are shown. *P<0.05; **P<0.001.