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. 2017 Nov 20;8(64):108118–108129. doi: 10.18632/oncotarget.22551

Table 1. The clinical characteristics of patients (n=273).

Characteristic N (%)
Age, years 53.9±10.6 (27-80)
 ≥70 18 (6.59)
 <70 255 (93.41)
Gender
 Male 91 (33.33)
 Female 182 (66.67)
Smoking history
 Yes 216 (79.12)
 No 57 (20.88)
Tumor size
 >6mm 16 (5.86)
 6-8mm 47 (17.22)
 <8mm 210 (76.92)
Histologic types
 Benign 65 (23.81)
  AAH 23 (8.42)
  Inflammatory cell infiltration 19 (6.96)
  Hyperplasia of fibrous tissue 15 (5.49)
  Granulomas 5 (1.83)
  Hamartomas 3 (1.10)
 Malignant 208 (76.19)
  AIS 130 (47.62)
  MIA 23 (8.42)
  IA 55 (20.15)
Increased serum tumor marker
 CEA 4 (1.47)
 CYFRA 21-1 58 (21.25)

CEA: carcinoembryonic antigen; CYFRA 21-1: cytokeratin 19 fragments, AAH: atypical adenomatous hyperplasia; AIS: adenocarcinoma in situ; MIA: minimally invasive adenocarcinoma; IA: invasive adenocarcinoma.