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. 2017 Oct 24;7(1):98–108. doi: 10.1002/sctm.17-0071

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© 2017 The Authors Stem Cells Translational Medicine published by Wiley Periodicals, Inc. on behalf of AlphaMed Press

This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Thermography. (A): Thermographic data were analyzed according to core wound temperature (small square gates centered on wounds) and overall Leg temperature (larger square gates). (B): A significant effect of time was detected for all groups (p < .0001). By 6 weeks, the difference between core wound and surrounding leg temperature is nearly zero, that is, temperature of the wound bed has normalized. There was a significant decrease of temperature variation in wounds treated with mesenchymal stem cell (MSC) embedded gels and injected MSCs at Week 6. Data are displayed as mean (SE). Week 0 data was collected on day 1 after wounding, prior to treatment application. Symbols: * denotes statistically significant difference for Injection (*, p < .05; **, p < .01; ***, p < .001); # denotes statistically significant difference for Gel (#, p < .05; ##, p < .01).