Table 6.
Stereological estimates in postmortem schizophrenia studies of other thalamic nuclei.
| Authors (year) | Brain banka | Region(s) | Schiz/Cont/Otherb | Mean age (years) | Estimatesc | Reported significant schiz. related diff.d |
|---|---|---|---|---|---|---|
| Popken et al. (2000) | 6 | Left: ventral posterior medial n. | 5M1F/5M1F | 66.0/64.0 | V, N(neu), Nv(neu) | No differences |
| Danos et al. (2002) | 3 | Right and left ventral lateral posterior n. | 5M3F/5M3F | 52.3/55.4 | V, N(neu), NV(neu) | Left side only: Decreased V 25% & N 27% |
| Byne et al. (2002) | 1 | Right centeromedian n. | 4M6F/4M1Fe | 66.6/75.0 | V | No differences |
| Byne et al. (2008) | 8 | Right orf left centeromedian n. | 7M3F2?/8M6F/7M6F/8M5F1?f | 43.3/48.6/46.8/42.3g | V | No differences |
| Selemon & Begovic (2007) | 8 | Right orh left lateral geniculate n.: magnocellular, and parvocellular layers | 9M6F/9M6F | 44.5/48.1 | V, N(neu, glia) | No differences |
| Dorph-Petersen et al. (2009) | 9 | Left: lateral geniculate n. (LGN) incl. magno - (M) and parvo - (P) cellular laminae and interlaminar regions (I) | 6M3F/5M2F/8M5Fi | 44.8/50.6/53.3i | V: LGN, M, P, I; N(neu): LGN, M, P | No differences |
Positive findings in bold.
Brain bank according to Table 1.
Number of males (M) and females (F) in each diagnostic group: Schizophrenia (Schiz), Control (Cont) group, Other diagnostic group(s).
Abbreviations: V volume; N number; NV numerical density; neu neuron. Regions are abbreviated as in the “Region(s)” column.
Statistically significant differences for the schizophrenia group. Abbreviations as in “Estimates” column.
“Restricted” subject groups without Alzheimer’s type pathology. The results listed are for these subjects without Alzheimer’s type pathology. Full subject sample: 14 Schiz, 8 Cont.
Schiz 4R6L2?; Cont 6R8L; Major Depression (MDD) 6R7L; Bipolar Disorder (BPD) 7R6L1?. Two Schiz & one BPD excluded without details from the full study sample of 14 Schiz, 14 Cont, 13 MDD, and 15 BPD. Thus, side and sex not reported for three subjects. R right, L left.
Mean ages for the full study sample of 14 + 14 + 13 + 15 subjects.
Schiz 9R6L; Cont 8R7L.
Mood disorder group.