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. Author manuscript; available in PMC: 2017 Dec 28.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2012 Apr 27;84(2):437–442. doi: 10.1016/j.ijrobp.2012.02.034

Table 6. Acute and Late Xerostomia.

Acute Xerostomia Late Xerostomia
Study Grade 1 Grade 2 Time point Grade 2
RTOG 0244 25.6% 20.9% 1 year 5.9%
RTOG 0022 (IMRT) 38.8% 49.3% 1 year 22.7%
Brizel et al. phase III amifostine study NR 51% 1 year 34%
Koukourakis et al. s/C amifostine, phase II study NR 58% NR NR
Lee et al. (IMRT), UCSF experience 28% 64% NR NR
Buentzel et al. I/V (amifostine), phase III study 46% 39% >90 days 39%
Nangia et al. (IMRT), IJROBP, 2010 NR NR >1 year 36%
Vergee et al. (IMRT), IJROBP, 2009 NR NR 6 months 32%
Wasserman et al.I/V (amifostine), IJROBP, 2005 NR NR 1 year 34%

NR = not reported for all patients on the study.