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. 2017 Oct 31;41(1):51–60. doi: 10.3892/ijmm.2017.3226

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Copyright: © Luo et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Effect of cell-based gene transfer on hemodynamic parameters and pulmonary vascular remodeling in the rats with pulmonary arterial hypertension (PAH). (A) Mean pulmonary arterial pressure (mPAP). (B) Wall to lumen thickness (WT%) in the Ctr, PAH, adipose-derived stem cells (ADSCs), ADSCs-V and ADSCs-adiponectin (APN) groups. ^*P<0.05 vs. Ctr group; ^#P<0.05 vs. PAH group; ^△P<0.05 vs. ADSCs group. (C) Representative pulmonary arteries with H&E staining. Scale bars, 50 μm. (D) Representative pulmonary arteries immunostained with α-smooth muscle actin (α-SMA) antibody. Scale bars, 50 μm.