Figure 5.

Prop attenuates ISO-stimulated Cal27 and SCC15 cell migration and invasion by inhibiting ISO-induced epithelial mesenchymal transition. Representative, (A) ISO increased cells migration and invasion and attenuated by Prop in Cal27 and (B) SCC15. Western blot analysis indicated that, (C) in Cal27 and (D) SCC15 cells, E-cadherin expression was downregulated and vimentin expression was upregulated in ISO exposed groups than controls. Error bars represent the standard deviation; ^*P<0.05. Prop, propranolol; ISO, isoproterenol.