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. 2017 Nov 9;41(1):147–154. doi: 10.3892/ijmm.2017.3248

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Copyright: © Liu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Activation of β2-AR promoted epithelial mesenchymal transition in Cal27 and SCC15 cells through initiating IL-6/Stat3/Snail1 pathway. (A) Expression of IL-6, Stat3, p-Stat3 and Snail1 in Cal27 and SCC15 cells treated by ISO with or without ICI-118,551. (B) Expression of IL-6, Stat3, p-Stat3 and Snail1 in the presence of IL-6 mAb, ISO and ICI-118,551. ISO, isoproterenol; β2-AR, β2-adrenergic receptor; IL-6, interleukin-6; mAb, monoclonal antibody; Stat3, signal transducer and activator of transcription 3; p-, phospho.