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. 2017 Nov 2;41(1):284–292. doi: 10.3892/ijmm.2017.3233

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Copyright: © Gu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Expression levels of miR-130b in glioma tissues and cell lines. (A) miR-130b was detected in 30 glioma tissues and 5 non-neoplastic brain specimens by reverse transcription-quantitative polymerase chain reaction. miR-130b expression was significantly higher in the glioma tissues compared with the non-neoplastic brain specimens, and the expression in the high level glioma groups is higher than in the low level group. ^*P<0.05 vs. non-neoplastic brain specimens; ^#P<0.05 vs. WHO I/II group. (B) miR-130b expression was detected in LN229, U87 and U251 glioma cell lines and primary NHAs. qPCR showed that miR-130b was upregulated in all of the glioma cell lines compared with the NHA cells. ^*P<0.05 vs. NHA cells. NHA, normal human astrocytes.