Skip to main content
. 2017 Nov 9;41(1):251–263. doi: 10.3892/ijmm.2017.3245

Figure 5.

Figure 5

Effects of LSE on the ability of spatial learning and memory in type 2 diabetes mellitus rats with cognitive impairment induced by HFSP diet and (STZ, 27 mg/kg, intraperitoneal ×1). Detail running tracts: (A) Normal rats on regular diet (control) treated with NS (1 ml/kg/day, IG ×28); (B) rats on HFSP diet and treated with STZ and NS (1 ml/kg/day, IG ×28); (C) rats on HFSP diet and treated with STZ and donepezil (0.42 mg/kg/day, IG ×28); (D) rats on HFSP diet and treated with STZ and LSE (0.7 g/kg/day, IG ×28); (E) rats on HFSP diet and treated with STZ and LSE (1.4 g/kg/day, IG ×28); and (F) rats on HFSP diet and treated with STZ and LSE (2.8 g/kg/day, IG ×28). There were 10 rats used for each experimental group. 1, First quadrant; 2, beta quadrant; 3, third quadrant; 4, delta quadrant. LSE, lychee seed extract; HFSP, high fat, high sugar and high protein; STZ, streptozotocin; NS, normal saline; IG, intragastric.