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. 2017 Oct 25;41(1):173–183. doi: 10.3892/ijmm.2017.3210

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Copyright: © Yao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Osteogenic differentiation of SFCs and SSSCs. Calcium deposits were confirmed by Alizarin Red S staining in (A, B, E, F, I and J) SFCs and (C, D, G, H, K and L) SSSCs. Scale bars, 100 μm. qPCR results for (M) RUNX-2, (N) OCN, and (O) ALP expression in SFCs and SSSCs compared with those in the corresponding control groups. ^*P<0.05, ^**P<0.01. ALP, alkaline phosphatase; OCN, osteocalcin; RUNX-2, runt-related transcription factor 2; SFCs, synovial fragment cells; SSSCs, surgery-obtained synovium specimen cells.