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. 2017 Oct 27;41(1):220–232. doi: 10.3892/ijmm.2017.3220

Figure 7.

Figure 7

Representative measurements of the SMAD3 TSS1500 methylation status. (A) The TSS1500 methylation frequency of SMAD3 in 81 patients with ACS, 74 patients with SCAD and 53 healthy individuals was measured using methylation-specific semi-quantitative polymerase chain reaction analysis. (B) The DNA methylation level of SMAD3 TSS1500 using Sequenom MassARRAY in 8 paired ACS, SCAD and healthy individuals was measured. SMAD3, mothers against decapentaplegic homolog 3; MM, fully methylated; MU, methylated/unmethylated or semi-methylated; ACS, acute coronary syndrome; SCAD, stable coronary artery disease.