Table IX.

List of the top 19 hypermethylated and 17 hypomethylated corresponding genes selected as possible diagnostic markers.

A, Hypermethylated corresponding genes
CpG site	ACS vs. control group methylation β score difference	Gene affected	P-value	FDR
cg03951394	0.31859	DEAF1	4.61×10−2	0.43464
cg11478607	0.33696	GSTT1	1.43×10−3	0.24422
cg01387905	0.34720	ADAMTS2	1.35×10−6	0.03278
cg13829625	0.35709	SIN3B	1.13×10−6	0.03160
cg18424635	0.35947	HLA-DRB5	2.83×10−2	0.39069
cg26951705	0.38792	ZNF787	4.81×10−2	0.43861
cg00243527	0.39404	LIF	4.99×10−2	0.44222
cg23782583	0.40248	JAKMIP3	4.53×10−2	0.43270
cg00248861	0.40500	WHSC2	3.01×10−2	0.39564
cg17005068	0.41609	GSTT1	1.49×10−5	0.14324
cg10662395	0.46909	HCN2	3.48×10−3	0.24464
cg19235645	0.47402	FAM101A	4.16×10−2	0.42548
cg21829038	0.48534	LRRK1	3.54×10−2	0.41016
cg17713488	0.49270	COL5A3	7.66×10−5	0.24422
cg14594459	0.50806	PKHD1L1	4.34×10−2	0.42957
cg18443741	0.79680	PYROXD1	2.48×10−5	0.18747
cg19577958	0.54856	SERPINB9	4.46×10−2	0.43166
cg04234412	0.64833	LOC391322	3.49×10−7	0.01914
cg16836675	0.68159	TOM1L1	4.18×10−3	0.24951
B, Hypomethylated corresponding genes
cg20592836	−0.59591	TP53INP2	1.33×10−2	0.32577
cg03549208	−0.55680	ICA1L	3.62×10−2	0.41253
cg27141807	−0.53542	SPSB4	2.27×10−2	0.37233
cg24851651	−0.48666	CCS	1.31×10−2	0.32488
cg06180910	−0.43609	GSTT1	1.11×10−4	0.24422
cg10864200	−0.41318	PCGF3	1.12×10−2	0.31160
cg24875593	−0.40991	PDXK	5.26×10−3	0.26054
cg04613734	−0.39972	TRPS1	4.07×10−2	0.42315
cg19961153	−0.38234	ALPPL2	4.02×10−2	0.42219
cg05141159	−0.37248	DEXI	3.71×10−2	0.41476
cg06049774	−0.34306	PLAC9	9.33×10−3	0.29687
cg23231631	−0.33541	GABRB1	3.02×10−6	0.05052
cg23731272	−0.32429	SMAD3	5.37×10−3	0.26137
cg08253809	−0.32072	C14orf119	3.87×10−2	0.41857
cg01655658	−0.31142	HLA-L	4.82×10−7	0.02123
cg13120108	−0.31114	PRKCH	4.08×10−2	0.42353
cg20433858	−0.30584	OR2L13	3.36×10−3	0.24464

CpG, 5′-C-phosphate-G-3′; ACS, acute coronary syndrome; FDR, false discovery rate.